Product details
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VAMP2 rabbit pAb
Ucallm_WP6074-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | VAMP2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 13kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human VAMP2 |
| Specificity | This antibody detects endogenous levels of VAMP2 at Human, Mouse,Rat |
| Gene Name | VAMP2 SYB2 |
| Protein Name | Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2) |
| Other Name | |
| Species | Human |
| Gene ID | 6844 |
| Uniprot | P63027, |
| Species.1 | Mouse |
| Gene ID.1 | 22318 |
| Uniprot.1 | P63044, |
| Species.2 | Rat |
| Gene ID.2 | 24803 |
| Uniprot.2 | P63045 |
| Cellular Localization | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein . Cell membrane . Colocalizes with PRKCZ and WDFY2 in intracellular vesicles (PubMed:17313651). . |
| Tissue Expression | Nervous system and skeletal muscle. |
| Signaling_pathway | Organismal Systems >> Endocrine system >> Insulin secretion;Organismal Systems >> Nervous system >> Synaptic vesicle cycle |
| Research Areas | |
| Function | Involved in the targeting and/or fusion of transport vesicles to their target membrane (By similarity). Major SNARE protein of synaptic vesicles which mediates fusion of synaptic vesicles to release neurotransmitters. Essential for fast vesicular exocytosis and activity-dependent neurotransmitter release as well as fast endocytosis that mediates rapid reuse of synaptic vesicles (By similarity) . Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. |
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