Product details
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KIF2A rabbit pAb
Ucallm_WP6375-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | KIF2A |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 78kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human KIF2A |
| Specificity | This antibody detects endogenous levels of KIF2A at Human, Mouse,Rat |
| Gene Name | KIF2A KIF2 KNS2 |
| Protein Name | Kinesin-like protein KIF2A (Kinesin-2) (hK2) |
| Other Name | |
| Species | Human |
| Gene ID | 3796 |
| Uniprot | O00139, |
| Species.1 | Mouse |
| Gene ID.1 | 16563 |
| Uniprot.1 | P28740, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q9WV63 |
| Cellular Localization | Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity. |
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