Product details
Background:
AHI1 rabbit pAb
Ucallm_WP6535-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | AHI1 |
| Reactivity | Human, Rat |
| Applications | WB |
| MW(Calculated) | 132kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human AHI1 |
| Specificity | This antibody detects endogenous levels of AHI1 at Human,Rat |
| Gene Name | AHI1 |
| Protein Name | Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1) |
| Other Name | |
| Species | Human |
| Gene ID | 54806 |
| Uniprot | Q8N157, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8K3E5, |
| Species.2 | Rat |
| Gene ID.2 | 308923 |
| Uniprot.2 | Q6DTM3 |
| Cellular Localization | Cytoplasm, cytoskeleton, cilium basal body . Cell junction, adherens junction . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . In the retinal photoreceptor cell layer, localizes at the connecting cilium. . |
| Tissue Expression | Highly expressed in the most primitive normal hematopoietic cells. Expressed in brain, particularly in neurons that give rise to the crossing axons of the corticospinal tract and superior cerebellar peduncles. Expressed in kidney (renal collecting duct cells) (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation. As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development . |
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