Product details
Background:
FMNL1 rabbit pAb
Ucallm_WP6811-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | FMNL1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 121kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human FMNL1 |
| Specificity | This antibody detects endogenous levels of FMNL1 at Human, Mouse |
| Gene Name | FMNL1 C17orf1 C17orf1B FMNL |
| Protein Name | Formin-like protein 1 (CLL-associated antigen KW-13) (Leukocyte formin) |
| Other Name | |
| Species | Human |
| Gene ID | 752 |
| Uniprot | O95466, |
| Species.1 | Mouse |
| Gene ID.1 | 57778 |
| Uniprot.1 | Q9JL26 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Cell membrane; Lipid-anchor . Cytoplasmic vesicle, phagosome . Recruited to actin-rich phagosomes during phagocytosis. Translocates to the plasma membrane upon activation by RAC1 (By similarity). .; [Isoform 3]: Cytoplasm, cell cortex. Cell projection, bleb. Colocalized with F-actin in bleb protrusions. |
| Tissue Expression | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Signaling_pathway | |
| Research Areas | |
| Function | May play a role in the control of cell motility and survival of macrophages (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. |
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