Product details
Background:
EIF2C1 rabbit pAb
Ucallm_WP6983-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | AGO1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 94kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human EIF2C1 |
| Specificity | This antibody detects endogenous levels of EIF2C1 at Human, Mouse |
| Gene Name | EIF2C1 AGO1 |
| Protein Name | Protein argonaute-1 (Argonaute1) (hAgo1) (Eukaryotic translation initiation factor 2C 1) (eIF-2C 1) (eIF2C 1) (Putative RNA-binding protein Q99) |
| Other Name | |
| Species | Human |
| Gene ID | 26523 |
| Uniprot | Q9UL18, |
| Species.1 | Mouse |
| Gene ID.1 | 236511 |
| Uniprot.1 | Q8CJG1 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm, P-body . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs). |
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