Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human SPRR1B
Specificity
This antibody detects endogenous levels of SPRR1B at Human, Mouse
Gene Name
SPRR1B
Protein Name
Cornifin-B (14.9 kDa pancornulin) (Small proline-rich protein IB) (SPR-IB)
Other Name
Species
Human
Gene ID
6699
Uniprot
P22528,
Species.1
Mouse
Gene ID.1
20754
Uniprot.1
Q62267
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm.
Tissue Expression
Suprabasal layers of squamous-differentiated tissues such as epidermis, esophagus, tongue and trachea.
Signaling_pathway
Research Areas
Function
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.