Price range: $268.00 through $328.00
Background:
This gene encodes a protein with a C-terminal Sprouty-like cysteine-rich domain (SRY) and an N-terminal Ena/Vasodilator-stimulated phosphoprotein (VASP) homology-1 (EVH-1) domain. The encoded protein is a member of a family of proteins that negatively regulates mitogen-activated protein (MAP) kinase signaling, particularly during organogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012],
| Size | 50μL/100μL |
| Target | SPRE3 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 45kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human SPRE3 AA range: 311-361 |
| Specificity | This antibody detects endogenous levels of SPRE3 at Human/Mouse |
| Gene Name | SPRED3 EVE-3 |
| Protein Name | SPRE3 |
| Other Name | |
| Species | Human |
| Gene ID | 399473 |
| Uniprot | Q2MJR0, |
| Species.1 | Mouse |
| Gene ID.1 | 101809 |
| Uniprot.1 | Q6P6N5 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Peripheral membrane protein . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase.,PTM:Phosphorylated on tyrosine.,similarity:Contains 1 SPR (sprouty) domain.,similarity:Contains 1 WH1 domain.,subunit:Interacts with Ras., |
