Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human WDR74
Specificity
This antibody detects endogenous levels of WDR74 at Human, Mouse
Gene Name
WDR74 NSA1
Protein Name
WD repeat-containing protein 74 (NOP seven-associated protein 1)
Other Name
Species
Human
Gene ID
54663
Uniprot
Q6RFH5,
Species.1
Mouse
Gene ID.1
107071
Uniprot.1
Q8VCG3
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Nucleus, nucleolus . Nucleus . Nucleolar location depends on active PolI transcription of pre-rRNA. .
Tissue Expression
Signaling_pathway
Research Areas
Function
Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit . Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL . Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development (By similarity).