Product details
Background:
ASGR2 rabbit pAb
Ucallm_WP8132-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ASGR2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 34kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ASGR2 |
| Specificity | This antibody detects endogenous levels of ASGR2 at Human, Mouse,Rat |
| Gene Name | ASGR2 CLEC4H2 |
| Protein Name | Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (C-type lectin domain family 4 member H2) (Hepatic lectin H2) (HL-2) |
| Other Name | |
| Species | Human |
| Gene ID | 433 |
| Uniprot | P07307, |
| Species.1 | Mouse |
| Gene ID.1 | 11890 |
| Uniprot.1 | P24721, |
| Species.2 | Rat |
| Gene ID.2 | 29403 |
| Uniprot.2 | P08290 |
| Cellular Localization | Membrane; Single-pass type II membrane protein. |
| Tissue Expression | Expressed exclusively in hepatic parenchymal cells. |
| Signaling_pathway | |
| Research Areas | |
| Function | Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. |
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