SKU: WP8208 Categories: ,

HPSE2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8208-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetHPSE2
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)65kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human HPSE2
SpecificityThis antibody detects endogenous levels of HPSE2 at Human, Mouse
Gene NameHPSE2 HPA2
Protein NameInactive heparanase-2 (Hpa2)
Other Name
SpeciesHuman
Gene ID60495
UniprotQ8WWQ2,
Species.1Mouse
Gene ID.1545291
Uniprot.1B2RY83
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationSecreted, extracellular space, extracellular matrix .
Tissue ExpressionWidely expressed, with the highest expression in brain, mammary gland, prostate, small intestine, testis and uterus. In the central nervous system, expressed in the spinal chord, caudate nucleus, thalamus, substantia nigra, medulla oblongata, putamen and pons. In the urinary bladder, expressed in longitudinal and circular layers of detrusor muscle. Found both in normal and cancer tissues.
Signaling_pathway
Research Areas
FunctionBinds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro).
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