Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human C16orf84
Specificity
This antibody detects endogenous levels of C16orf84 at Human, Mouse,Rat
Gene Name
CTU2 C16orf84 NCS2
Protein Name
Cytoplasmic tRNA 2-thiolation protein 2
Other Name
Species
Human
Gene ID
348180
Uniprot
Q2VPK5,
Species.1
Mouse
Gene ID.1
66965
Uniprot.1
Q3U308,
Species.2
Rat
Gene ID.2
292069
Uniprot.2
Q3B7U4
Cellular Localization
Cytoplasm.
Tissue Expression
Signaling_pathway
Genetic Information Processing >> Folding, sorting and degradation >> Sulfur relay system
Research Areas
Function
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.