Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human WIPF2
Specificity
This antibody detects endogenous levels of WIPF2 at Human, Mouse
Gene Name
WIPF2 WICH WIRE PP10631
Protein Name
WAS/WASL-interacting protein family member 2 (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein) (WIP-related protein)
Other Name
Species
Human
Gene ID
147179
Uniprot
Q8TF74,
Species.1
Mouse
Gene ID.1
68524
Uniprot.1
Q6PEV3
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm, cytoskeleton . Localized to stress fibers and bundles of actin filaments.
Tissue Expression
Expressed mainly in brain, colon, lung and stomach (at protein level). Ubiquitously expressed, with high expression in brain, kidney, lung, and placenta.
Signaling_pathway
Research Areas
Function
Plays an active role in the formation of cell surface protrusions downstream of activated PDGFB receptors. Plays an important role in actin-microspike formation through cooperation with WASL. May cooperate with WASP and WASL to induce mobilization and reorganization of the actin filament system.