Name: ABCB10 Polyclonal Antibody
SKU: WP10881
Price: 268 USD
Availability: InStock

ABCB10 Polyclonal Antibody

Ucallm_WP10881-50

Price range: $268.00 through $328.00

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100μl

50μl

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SKU: WP10881-100

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Product details

Background:

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown. [provided by RefSeq, Jul 2008],

Specifications

Target	ABCB10
Reactivity	Human, Mouse
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	79kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Modification
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human ABCB10. AA range:441-490
Sequence
Specificity	ABCB10 Polyclonal Antibody detects endogenous levels of ABCB10 protein.
Gene Name	ABCB10
Protein Name	ATP-binding cassette sub-family B member 10 mitochondrial
Other Name	ABCB10; / ATP-binding cassette sub-family B member 10; / mitochondrial; / ATP-binding cassette transporter 10; / ABC transporter 10 protein; / Mitochondrial ATP-binding cassette 2; / M-ABC2
Species	Human
Gene ID-1	23456
Uniprot	Q9NRK6,
Species.1	Mouse
Gene ID-2
Uniprot.1	Q9JI39
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Background	The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown. [provided by RefSeq, Jul 2008],
Cellular Localization	Mitochondrion inner membrane; Multi-pass membrane protein .
Tissue Expression	Ubiquitous. Highly expressed in bone marrow, expressed at intermediate to high levels in skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph node, trachea and adrenal gland, and low levels are found in lung, kidney, spleen, thymus and colon.
Signaling_pathway
Research Areas	>>ABC transporters
Function	Function:May mediate critical mitochondrial transport functions related to heme biosynthesis.,similarity:Belongs to the ABC transporter family.,similarity:Belongs to the ABC transporter family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily.,similarity:Contains 1 ABC transmembrane type-1 domain.,similarity:Contains 1 ABC transporter domain.,subunit:Homodimer or heterodimer .,tissue specificity:Ubiquitous. Highly expressed in bone marrow, expressed at intermediate to high levels in skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph node, trachea and adrenal gland, and low levels are found in lung, kidney, spleen, thymus and colon.,
RRID