ABCB10 Polyclonal Antibody
Ucallm_WP10881-50
Price range: $268.00 through $328.00
Product details
Background:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | ABCB10 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 79kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ABCB10. AA range:441-490 |
| Specificity | ABCB10 Polyclonal Antibody detects endogenous levels of ABCB10 protein. |
| Gene Name | ABCB10 |
| Protein Name | ATP-binding cassette sub-family B member 10 mitochondrial |
| Other Name | ABCB10; / ATP-binding cassette sub-family B member 10; / mitochondrial; / ATP-binding cassette transporter 10; / ABC transporter 10 protein; / Mitochondrial ATP-binding cassette 2; / M-ABC2 |
| Species | Human |
| Gene ID | 23456 |
| Uniprot | Q9NRK6, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9JI39 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Mitochondrion inner membrane; Multi-pass membrane protein . |
| Tissue Expression | Ubiquitous. Highly expressed in bone marrow, expressed at intermediate to high levels in skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph node, trachea and adrenal gland, and low levels are found in lung, kidney, spleen, thymus and colon. |
| Signaling_pathway | |
| Research Areas | >>ABC transporters |
| Function | Function:May mediate critical mitochondrial transport functions related to heme biosynthesis.,similarity:Belongs to the ABC transporter family.,similarity:Belongs to the ABC transporter family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily.,similarity:Contains 1 ABC transmembrane type-1 domain.,similarity:Contains 1 ABC transporter domain.,subunit:Homodimer or heterodimer .,tissue specificity:Ubiquitous. Highly expressed in bone marrow, expressed at intermediate to high levels in skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph node, trachea and adrenal gland, and low levels are found in lung, kidney, spleen, thymus and colon., |
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