Price range: $268.00 through $328.00
Background:
The protein encoded by this gene is a single-pass type I membrane protein of unknown function that contains several EGF-like domains, Kelch repeats, and PSI domains. Defects in this gene are a cause of Carpenter syndrome 2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],
| Size | 50μL/100μL |
| Target | EGFL4 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 255kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MEGF8. AA range:1243-1292 |
| Specificity | EGFL4 Polyclonal Antibody detects endogenous levels of EGFL4 protein. |
| Gene Name | MEGF8 |
| Protein Name | Multiple epidermal growth factor-like domains protein 8 |
| Other Name | MEGF8; / C19orf49; / EGFL4; / KIAA0817; / Multiple epidermal growth factor-like domains protein 8; / Multiple EGF-like domains protein 8; / Epidermal growth factor-like protein 4; / EGF-like protein 4 |
| Species | Human |
| Gene ID | 1954 |
| Uniprot | Q7Z7M0, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P60882 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Single-pass type I membrane protein . |
| Tissue Expression | Brain,Pancreas,Plasma, |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> Hedgehog signaling pathway |
| Research Areas | >>Hedgehog signaling pathway |
| Function | similarity:Contains 12 Kelch repeats.,similarity:Contains 2 CUB domains.,similarity:Contains 4 laminin EGF-like domains.,similarity:Contains 5 EGF-like domains.,similarity:Contains 7 PSI domains., |
