Price range: $268.00 through $328.00
Background:
This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq, Jan 2009],
| Size | 50μL/100μL |
| Target | Tubulin γ |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 51kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Tubulin gamma. AA range:386-435 |
| Specificity | Tubulin γ Polyclonal Antibody detects endogenous levels of Tubulin γ protein. |
| Gene Name | TUBG1 |
| Protein Name | Tubulin gamma-1 chain |
| Other Name | TUBG1; / TUBG; / Tubulin gamma-1 chain; / Gamma-1-tubulin; / Gamma-tubulin complex component 1; / GCP-1 |
| Species | Human |
| Gene ID | 7283 |
| Uniprot | P23258, |
| Species.1 | Mouse |
| Gene ID.1 | 103733 |
| Uniprot.1 | P83887, |
| Species.2 | Rat |
| Gene ID.2 | 252921 |
| Uniprot.2 | P83888 |
| Cellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Localizes to mitotic spindle microtubules. . |
| Tissue Expression | Mammary cancer,Skin, |
| Signaling_pathway | |
| Research Areas | >>Human papillomavirus infection |
| Function | Function:Tubulin is the major constituent of microtubules. Gamma tubulin is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.,mass spectrometry: PubMed:11840567,similarity:Belongs to the tubulin family.,subunit:Interacts with GCP2 and GCP3. Interacts with B9D2., |
