Price range: $268.00 through $328.00
Background:
This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Feb 2012],
| Size | 50μL/100μL |
| Target | UMP-CMP Kinase |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 22kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human KCY. AA range:1-50 |
| Specificity | UMP-CMP Kinase Polyclonal Antibody detects endogenous levels of UMP-CMP Kinase protein. |
| Gene Name | CMPK1 |
| Protein Name | UMP-CMP kinase |
| Other Name | CMPK1; / CMK; / CMPK; / UCK; / UMK; / UMPK; / UMP-CMP kinase; / Cytidine monophosphate kinase; / Cytidylate kinase; / Deoxycytidylate kinase; / Uridine monophosphate kinase; / Uridine monophosphate/cytidine monophosphate kinase; / UMP/CMP kinase; / UMP/CMPK |
| Species | Human |
| Gene ID | 51727 |
| Uniprot | P30085, |
| Species.1 | Mouse |
| Gene ID.1 | 66588 |
| Uniprot.1 | Q9DBP5, |
| Species.2 | Rat |
| Gene ID.2 | 298410 |
| Uniprot.2 | Q4KM73 |
| Cellular Localization | Nucleus . Cytoplasm . Predominantly cytoplasmic, less than 15% nuclear. . |
| Tissue Expression | Ubiquitously expressed. |
| Signaling_pathway | |
| Research Areas | >>Pyrimidine metabolism; / >>Drug metabolism - other enzymes; / >>Metabolic pathways; / >>Nucleotide metabolism; / >>Biosynthesis of cofactors |
| Function | Catalytic activity:ATP + (d)CMP = ADP + (d)CDP.,cofactor:Magnesium.,Function:Catalyzes specific phosphoryl transfer from ATP to UMP and CMP.,similarity:Belongs to the adenylate kinase family.,subcellular location:Mainly nuclear.,tissue specificity:Ubiquitously expressed., |
