Price range: $268.00 through $328.00
Background:
TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 [PubMed 10965142]).[supplied by OMIM, Mar 2008],
| Size | 50μL/100μL |
| Target | TBCD1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 128kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TBCD1 AA range: 716-766 |
| Specificity | This antibody detects endogenous levels of TBCD1 at Human/Mouse |
| Gene Name | TBC1D1 KIAA1108 |
| Protein Name | TBCD1 |
| Other Name | |
| Species | Human |
| Gene ID | 23216 |
| Uniprot | Q86TI0, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q60949 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> AMPK signaling pathway |
| Research Areas | >>AMPK signaling pathway |
| Function | Function:May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues.,similarity:Contains 1 PID domain.,similarity:Contains 1 Rab-GAP TBC domain., |
