Price range: $268.00 through $328.00
Background:
ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007 [PubMed 17210950]).[supplied by OMIM, Sep 2008],
| Size | 50μL/100μL |
| Target | ATD3A |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | 70kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ATD3A AA range: 433-483 |
| Specificity | This antibody detects endogenous levels of ATD3A at Human |
| Gene Name | ATAD3A |
| Protein Name | ATD3A |
| Other Name | |
| Species | Human |
| Gene ID | 55210 |
| Uniprot | Q9NVI7 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Mitochondrion inner membrane; Single-pass membrane protein . Mitochondrion matrix, mitochondrion nucleoid . In the mitochondrial inner membrane, enriched in sites with the potential to form contacts with the outer membrane (PubMed:20349121, PubMed:20154147). The N-terminal domain interacts with the inner surface of the mitochondrial outer membrane and the C-terminal domain localizes in a specific matrix compartment, where it is associated with nucleoids (PubMed:18063578). . |
| Tissue Expression | Overexpressed in lung adenocarcinomas (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Belongs to the AAA ATPase family., |
