2-Hydroxyisobutyryllysine Specific Antibody Conjugated Agarose Beads
Ucallm_WT9158B-100
$999.00
Product details
2-Hydroxyisobutyryllysine Specific Antibody Conjugated Agarose Beads is an immunoaffinity enrichment tool for 2-hydroxyisobutyryllysine peptides in mass spectrometry-based proteomics. The highly specific antibody selectively captures target modified peptides without cross-reactivity, is applicable to all species, efficiently enriches low-abundance peptides and reduces background interference, delivering stable and reliable results for 2-hydroxyisobutyryllysine modification research.
Specifications
| Target | 2-Hydroxyisobutyryllysine |
| Reactivity | Species Independent |
| Application | IAC, IAP, IP |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | |
| Isotype | |
| Conjugate | Agarose Beads |
| Modification | Lysine acylation |
| Modified site | Lys（K） |
| Recommended dilution ratio | |
| Composition | |
| Purification process | Protein A |
| Purity | |
| Storage | 50% slurry in PBS pH7.4, 0.05% Proclin 300. Ensure thorough mixing before each use. Wide-mouth pipette tips are recommended. In case of difficulty in aspiration due to improper operation, additional Storage Buffer can be added at your discretion. |
| Stability | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
| Clonal | Recombinant monoclonal |
| Clone Number | |
| Immunogen | |
| Sequence | |
| Specificity | |
| Gene name | |
| Protein Name | |
| Alternative name | Khib |
| Organism-1 | |
| GeneID-1 | |
| SwissProt-1 | |
| Organism-2 | |
| GeneID-2 | |
| SwissProt-2 | |
| Organism-3 | |
| GeneID-3 | |
| SwissProt-3 | |
| Organism-4 | |
| GeneID-4 | |
| SwissProt-4 | |
| Background | 2-Hydroxyisobutyryllysine (Khib) is a novel lysine acylation type of post_x001e_translational modification identified on both histone and non_x001e_histone proteins. By adding a 2-hydroxyisobutyryl group to lysine residues, Khib participates in the regulation of chromatin structure, gene transcription activation, cellular metabolism, and stress responses. Accumulating evidence indicates that Khib plays critical roles in tumorigenesis, metabolic reprogramming, inflammation, and various disease processes, making it an important target in epigenetic and protein modification research. |
| Cellular Localization |
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