Price range: $268.00 through $328.00
Background:
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. [provided by RefSeq, Jul 2008],
| Target | 5HT3C |
| Reactivity | Human |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 49kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | |
| Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000;ELISA 1:5000-20000 |
| Composition | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Source | |
| Purification Process | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage Condition | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 90-170 |
| Sequence | |
| Specificity | 5HT3C Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | HTR3C |
| Protein Name | 5-hydroxytryptamine receptor 3C (5-HT3-C) (5-HT3C) (Serotonin receptor 3C) |
| Alias | |
| Organism-1 | Human |
| Gene ID-1 | 170572 |
| SwissProt-1 | Q8WXA8 |
| Organism-2 | |
| Gene ID-2 | |
| SwissProt-2 | |
| Organism-3 | |
| Gene ID-3 | |
| SwissProt-3 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Cellular Localization | Cell membrane ; Multi-pass membrane protein . Presumably retained within the endoplasmic reticulum unless complexed with HTR3A. |
