Price range: $268.00 through $328.00
Background:
This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | A1AG1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 22kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 30-110 |
| Specificity | A1AG1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | ORM1 AGP1 |
| Protein Name | Alpha-1-acid glycoprotein 1 (AGP 1) (Orosomucoid-1) (OMD 1) |
| Other Name | |
| Species | Human |
| Gene ID | 5004 |
| Uniprot | P02763, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q60590 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted. |
| Tissue Expression | Expressed by the liver and secreted in plasma. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Appears to function in modulating the activity of the immune system during the acute-phase reaction.,induction:Synthesis is controlled by glucocorticoids, interleukin-1 and interleukin-6, It increases 5- to 50-fold upon inflammation.,polymorphism:Three common alleles of ORM1 are known. ORM1*F1 has Gln-38/Val-174; ORM1*F2 has Gln-38/Met-174 and ORM1*S has Arg-38/Val-174. The sequence shown is that of allele ORM1*F1.,similarity:Belongs to the calycin superfamily. Lipocalin family.,tissue specificity:Expressed by the liver and secreted in plasma., |
