Name: A1Up Polyclonal Antibody
SKU: WP10872
Price: 268 USD
Availability: InStock

A1Up Polyclonal Antibody

Ucallm_WP10872-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP10872-100

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Product details

Background:

PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 UBA domain., similarity:Contains 1 ubiquitin-like domain., subcellular location:May associate with the endoplasmic reticulum., subunit:Homodimer. Binds SCA1. Binds signal sequences of proteins that are targeted to the endoplasmic reticulum., tissue specificity:Highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver.,

Specifications

Target	A1Up
Reactivity	Human, Mouse
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	54kD
Host Species	Rabbit
Isotype	IgG
Conjugate
Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
Composition	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification Process	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage Condition	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human UBQLN4. AA range:201-250
Sequence
Specificity	A1Up Polyclonal Antibody detects endogenous levels of A1Up protein.
Gene Name	UBQLN4
Protein Name	Ubiquilin-4
Alias	UBQLN4;C1orf6;CIP75;UBIN;Ubiquilin-4;Ataxin-1 interacting ubiquitin-like protein;A1Up;Ataxin-1 ubiquitin-like-interacting protein A1U;Connexin43-interacting protein of 75 kDa;CIP75
Organism-1	Human
Gene ID-1	56893
SwissProt-1	Q9NRR5
Organism-2	Mouse
Gene ID-2	94232
SwissProt-2	Q99NB8
Organism-3
Gene ID-3
SwissProt-3
Organism-4
Gene ID-4
SwissProt-4
Cellular Localization	Nucleus . Cytoplasm . Chromosome . Endoplasmic reticulum . Cytoplasm, perinuclear region . Cytoplasmic vesicle, autophagosome . Colocalizes with the proteasome, both in nucleus and cytoplasm (PubMed:15280365). Exported from the nucleus following interaction with DESI1/POST (PubMed:29666234). In response to DNA damage and phosphorylation at Ser-318 by ATM, localizes to the nucleus and is recruited to sites of DNA damage (PubMed:30612738). .