SKU: WP0863 Categories: ,

AAT1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP0863-100
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Product details

Background:

alternative products:Additional isoforms (AAT-1L and AAT-1S) may exist, function:Isoform 4 may play a role in spermatogenesis., PTM:Isoform 4 is phosphorylated by PKA., subcellular location:Isoform 4 is found in the mitochondria and localized in the neck of the sperm., subunit:Interacts with AMY1 and AKAP1. Isoform 4 belongs to a complex together with AMY1, AKAP1 and PRKAR2B. Isoform 3 does not interact with AMY1., tissue specificity:Isoform 1 is strongly expressed in the liver. Isoform 4 is widely expressed, but strongly expressed in all spermatogenesis-related tissues, including the testis, the epithelium of cauda and the corpus epididymis. Isoform 4 is present in the spermatid and mature sperm. Isoform 4 is also expressed in Leydig cells. Isoform 3 is expressed in the testis.,

Specifications

Size50μL/100μL
TargetAAT1
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)66kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 310-390
SpecificityAAT1 Polyclonal Antibody detects endogenous levels of protein.
Gene NameAAT1 C3orf15
Protein NameAMY-1-associating protein expressed in testis 1 (AAT-1)
Other Name
SpeciesHuman
Gene ID89876
UniprotQ7Z4T9,
Species.1Mouse
Gene ID.1
Uniprot.1Q8BRC6
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMitochondrion . Cytoplasm . Cytoplasm, cytoskeleton, cilium axoneme . Localized in the neck of the sperm.; [Isoform 7]: Cytoplasm .
Tissue Expression[Isoform 1]: Strongly expressed in the liver.; [Isoform 7]: Widely expressed, but strongly expressed in all spermatogenesis-related tissues, including the testis, the epithelium of cauda and the corpus epididymis, as well as the spermatid and mature sperm. Also expressed in Leydig cells.
Signaling_pathway
Research Areas
FunctionAlternative products:Additional isoforms (AAT-1L and AAT-1S) may exist,Function:Isoform 4 may play a role in spermatogenesis.,PTM:Isoform 4 is phosphorylated by PKA.,subcellular location:Isoform 4 is found in the mitochondria and localized in the neck of the sperm.,subunit:Interacts with AMY1 and AKAP1. Isoform 4 belongs to a complex together with AMY1, AKAP1 and PRKAR2B. Isoform 3 does not interact with AMY1.,tissue specificity:Isoform 1 is strongly expressed in the liver. Isoform 4 is widely expressed, but strongly expressed in all spermatogenesis-related tissues, including the testis, the epithelium of cauda and the corpus epididymis. Isoform 4 is present in the spermatid and mature sperm. Isoform 4 is also expressed in Leydig cells. Isoform 3 is expressed in the testis.,
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