Price range: $268.00 through $328.00
Background:
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | ABC3C |
| Reactivity | Human |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 20kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 10-90 |
| Specificity | ABC3C Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | APOBEC3C APOBEC1L PBI |
| Protein Name | Probable DNA dC->dU-editing enzyme APOBEC-3C (APOBEC1-like) (Phorbolin I) |
| Other Name | |
| Species | Human |
| Gene ID | 27350 |
| Uniprot | Q9NRW3 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Cytoplasm . |
| Tissue Expression | Expressed in spleen, testes, peripherical blood lymphocytes, heart, thymus, prostate and ovary. |
| Signaling_pathway | |
| Research Areas | >>Viral life cycle - HIV-1; / >>Human immunodeficiency virus 1 infection |
| Function | cofactor:Zinc.,Function:Unknown. Unable to reduce HIV-1 infectivity in vitro.,miscellaneous:It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22.,similarity:Belongs to the cytidine and deoxycytidylate deaminase family.,tissue specificity:Expressed in spleen, testes, peripherical blood lymphocytes, heart, thymus, prostate and ovary., |
