ABCA9 Polyclonal Antibody
Ucallm_WP0901-50
Price range: $268.00 through $328.00
Product details
Background:
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | ABCA9 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 178kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 800-880 |
| Specificity | ABCA9 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | ABCA9 |
| Protein Name | ATP-binding cassette sub-family A member 9 |
| Other Name | |
| Species | Human |
| Gene ID | 10350 |
| Uniprot | Q8IUA7, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8K449 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Multi-pass membrane protein . |
| Tissue Expression | Widely expressed with higher expression in heart. |
| Signaling_pathway | |
| Research Areas | >>ABC transporters |
| Function | developmental stage:Expressed in fetal tissues with higher expression in fetal heart and kidney.,Function:May play a role in monocyte differentiation and lipid homeostasis.,induction:Up-regulated during monocyte differentiation into macrophages. Down-regulated by cholesterol loading of macrophages.,similarity:Belongs to the ABC transporter family. ABCA subfamily.,similarity:Contains 2 ABC transporter domains.,tissue specificity:Widely expressed with higher expression in heart., |
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