SKU: WR4972 Categories: ,

U-Blot® ACSS2 Rabbit mAb

Price range: $268.00 through $328.00

SKU: WR4972-50
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Product details

Background:This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009],

Specifications

Size50μL/100μL
TargetACSS2
ReactivityHuman, Mouse, Rat
ApplicationsWB, IF, ELISA
MW(Calculated)79kD
MW(Observed)79kD
Host SpeciesRabbit
IsotypeIgG,Kappa
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
PurificationRecombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberRM1204R
ImmunogenThe specific immunogen used to produce this antibody is proprietary information.
SpecificityEndogenous
Gene NameACSS2 ACAS2
Protein NameAcetyl-coenzyme A synthetase, cytoplasmic (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) (Acyl-activating enzyme)
Other Name
SpeciesHuman
Gene ID55902
UniprotQ9NR19,
Species.1Mouse
Gene ID.160525
Uniprot.1Q9QXG4
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm, cytosol .
Tissue ExpressionBlood,Melanoma,Muscle,Platelet,Skin,Tongue,
Signaling_pathway
Research Areas>>Glycolysis / Gluconeogenesis; / >>Pyruvate metabolism; / >>Glyoxylate and dicarboxylate metabolism; / >>Propanoate metabolism; / >>Metabolic pathways; / >>Carbon metabolism
FunctionCatalytic activity:ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.,Function:Activates acetate so that it can be used for lipid synthesis or for energy generation.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,subunit:Monomer.,
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