Product details
Background:
Adenylosuccinate lyase rabbit pAb
Ucallm_WP6809-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ADSL |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 53kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human Adenylosuccinate lyase |
| Specificity | This antibody detects endogenous levels of Adenylosuccinate lyase at Human, Mouse |
| Gene Name | ADSL AMPS |
| Protein Name | Adenylosuccinate lyase (ASL) (Adenylosuccinase) (ASase) |
| Other Name | |
| Species | Human |
| Gene ID | 158 |
| Uniprot | P30566, |
| Species.1 | Mouse |
| Gene ID.1 | 11564 |
| Uniprot.1 | P54822 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | |
| Tissue Expression | Ubiquitously expressed. Both isoforms are produced by all tissues. Isoform 2 is 10-fold less abundant than isoform 1. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate. |
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