Product details
Background:
ADM2 rabbit pAb
Ucallm_WP7720-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ADM2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 16kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ADM2 |
| Specificity | This antibody detects endogenous levels of ADM2 at Human, Mouse,Rat |
| Gene Name | ADM2 AM2 |
| Protein Name | ADM2 (Intermedin) [Cleaved into: Adrenomedullin-2 (AM2) (Intermedin-long) (IMDL); Intermedin-short (IMDS)] |
| Other Name | |
| Species | Human |
| Gene ID | 79924 |
| Uniprot | Q7Z4H4, |
| Species.1 | Mouse |
| Gene ID.1 | 223780 |
| Uniprot.1 | Q7TNK8, |
| Species.2 | Rat |
| Gene ID.2 | 399475 |
| Uniprot.2 | P61312 |
| Cellular Localization | Secreted. |
| Tissue Expression | Expressed in the esophagus, stomach, jejunum, ileum, ileocecum, ascending colon, transverse colon, descending colon and rectum. Expressed in myocardial cells of the heart, renal tubular cells, hypothalamus, and pituitary. |
| Signaling_pathway | Organismal Systems >> Circulatory system >> Vascular smooth muscle contraction |
| Research Areas | |
| Function | [Adrenomedullin-2]: May play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway.; [Intermedin-short]: May play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway. |
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