SKU: WP3879 Categories: ,

ADPRM rabbit pAb

Price range: $268.00 through $328.00

SKU: WP3879-100
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Product details

Background:

Specifications

TargetADPRM
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)38kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ADPRM AA range: 225-275
Sequence
SpecificityThis antibody detects endogenous levels of ADPRM at Human/Mouse/Rat
Gene NameADPRM C17orf48 MDS006 Nbla03831
Protein NameADPRM
Other Name
SpeciesHuman
Gene ID-156985
UniprotQ3LIE5,
Species.1Mouse
Gene ID-266358
Uniprot.1Q99KS6,
Species.2Rat
Gene ID-3287406
Uniprot.2Q5M886
Organism-4
Gene ID-4
SwissProt-4
Background
Cellular Localizationcytosol,integral component of membrane,
Tissue Expression
Signaling_pathway
Research Areas>>Purine metabolism; / >>Glycerophospholipid metabolism; / >>Metabolic pathways
FunctionCatalytic activity:ADP-ribose + H(2)O = AMP + D-ribose 5-phosphate.,Catalytic activity:CDP-choline + H(2)O = CMP + phosphocholine.,Catalytic activity:CDP-glycerol + H(2)O = CMP + sn-glycerol 3-phosphate.,cofactor:Magnesium.,Function:hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress.,similarity:Belongs to the ADPRibase-Mn family.,subunit:Monomer.,
RRID
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