Need Help? +(1)-866-986-9598
0 My Cart$0.00
Home/Reagents/Antibody/Primary antibody/Polyclonal Antibody/Rabbit pAb/ADT2 Polyclonal Antibody
SKU: WP0844 Categories: ,

ADT2 Polyclonal Antibody

Ucallm_WP0844-50

Price range: $268.00 through $328.00

SKU: WP0844-100
Enter the quantity you would like, or drag the panel to find the quantity and price that best for you
Bulk QuoteAuthorize OEM & ODM

Product details

Background:

This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013],

Specifications

Size50μL/100μL
TargetADT2
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)32kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 40-120
SpecificityADT2 Polyclonal Antibody detects endogenous levels of protein.
Gene NameSLC25A5 ANT2
Protein NameADP/ATP translocase 2 (ADP,ATP carrier protein 2) (ADP,ATP carrier protein, fibroblast isoform) (Adenine nucleotide translocator 2) (ANT 2) (Solute carrier family 25 member 5)
Other Name
SpeciesHuman
Gene ID292
UniprotP05141,
Species.1Mouse
Gene ID.1
Uniprot.1P51881,
Species.2Rat
Gene ID.2
Uniprot.2Q09073
Cellular LocalizationMitochondrion inner membrane; Multi-pass membrane protein . Membrane; Multi-pass membrane protein . May localize to non-mitochondrial membranes. .
Tissue ExpressionExpressed in erythrocytes (at protein level).
Signaling_pathwayCellular Processes >> Cell growth and death >> Necroptosis;Cellular Processes >> Cell growth and death >> Cellular senescence;Organismal Systems >> Immune system >> Neutrophil extracellular trap formation;Human Diseases >> Neurodegenerative disease >> Alzheimer disease;Human Diseases >> Neurodegenerative disease >> Parkinson disease;Human Diseases >> Neurodegenerative disease >> Huntington disease;Human Diseases >> Neurodegenerative disease >> Spinocerebellar ataxia;Human Diseases >> Neurodegenerative disease >> Prion disease;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases;Environmental Information Processing >> Signal transduction >> Calcium signaling pathway;Environmental Information Processing >> Signal transduction >> cGMP-PKG signaling pathway
Research Areas>>Calcium signaling pathway; / >>cGMP-PKG signaling pathway; / >>Necroptosis; / >>Cellular senescence; / >>Neutrophil extracellular trap formation; / >>Alzheimer disease; / >>Parkinson disease; / >>Huntington disease; / >>Spinocerebellar ataxia; / >>Prion disease; / >>Pathways of neurodegeneration - multiple diseases; / >>Influenza A; / >>Human T-cell leukemia virus 1 infection; / >>Chemical carcinogenesis - reactive oxygen species; / >>Diabetic cardiomyopathy
FunctionFunction:Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane.,miscellaneous:The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. Odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue.,similarity:Belongs to the mitochondrial carrier family.,similarity:Contains 3 Solcar repeats.,subunit:Homodimer. Interacts with HIV-1 Vpr.,
Please login to post questions

Related products
Sku: WR4007
Categories: ,

U-Blot® SQSTM1/p62 Rabbit mAb

0 Reviews
Price range: $268.00 through $328.00
Select options
Immunohistochemical analysis of paraffin-embedded Rat liver tissue. 1, primary Antibody was diluted at 1:200(4～C,overnight). 2, EDTA pH 9.0 was used for antibody retrieval(>98～C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min).
Sku: WR4010
Categories: ,

U-Blot® Glutamine Synthetase Rabbit mAb

0 Reviews
Price range: $268.00 through $328.00
Select options
Sku: WR4022
Categories: ,

U-Blot® GSK3 β (Phospho Ser9) Rabbit mAb

0 Reviews
Price range: $288.00 through $368.00
Select options
Sku: W2209
Categories: ,

U-Blot™ Phosphate Buffered Saline with Tween 20 (PBS-T), pH 7.4

0 Reviews
$199.00
Add to cartBulk Quote
Sku: WR4009
Categories: ,

U-Blot® VEGF Receptor 1 Rabbit mAb

0 Reviews
Price range: $268.00 through $328.00
Select options
Western blot analysis of lysates from NIH-3T3 cells, using GCLM Rabbit mAb. The HRP-conjugated Goat anti-Rabbit IgG antibody (WS0002) was used to detect the antibody.
Sku: WR4015
Categories: ,

U-Blot® MMP7 Rabbit mAb

0 Reviews
Price range: $268.00 through $328.00
Select options

Customer Reviews

  • Shop Categories
Menu
Need Help? +(1)-866-986-9598
Back to Top
Product has been added to your cart