Product details
Background:
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AF9 rabbit pAb
Ucallm_WP3561-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | AF9 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 60kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human AF9 AA range: 328-378 |
| Specificity | This antibody detects endogenous levels of AF9 at Human/Mouse |
| Gene Name | MLLT3 AF9 YEATS3 |
| Protein Name | AF9 |
| Other Name | Protein AF-9; / ALL1-fused gene from chromosome 9 protein; / Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein; / YEATS domain-containing protein 3 |
| Species | Human |
| Gene ID | 4300 |
| Uniprot | P42568, |
| Species.1 | Mouse |
| Gene ID.1 | 70122 |
| Uniprot.1 | A2AM29 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Chromosome . Colocalizes with acylated histone H3 (PubMed:25417107, PubMed:27105114). Colocalizes with histone H3 crotonylated at 'Lys-18' (H3K18cr) (PubMed:27105114). . |
| Tissue Expression | Enriched in undifferentiated hematopoietic stem cells in fetal liver, cord blood and bone marrow. |
| Signaling_pathway | Human Diseases >> Cancer: overview >> Transcriptional misregulation in cancer |
| Research Areas | >>Viral life cycle - HIV-1; / >>Transcriptional misregulation in cancer |
| Function | Disease:A chromosomal aberration involving MLLT3 is associated with acute leukemias. Translocation t(9; 11)(p22; q23) with MLL/HRX. The result is a rogue activator protein.,similarity:Contains 1 YEATS domain.,subunit:Interacts with BCOR. Interacts with CBX8., |
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