Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human AIDA
Specificity
This antibody detects endogenous levels of AIDA at Human, Mouse
Gene Name
AIDA C1orf80
Protein Name
Axin interactor, dorsalization-associated protein (Axin interaction partner and dorsalization antagonist)
Other Name
Species
Human
Gene ID
64853
Uniprot
Q96BJ3,
Species.1
Mouse
Gene ID.1
108909
Uniprot.1
Q8C4Q6
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Tissue Expression
Widely expressed in adult tissues, with highest expression in the heart and skeletal muscle.
Signaling_pathway
Research Areas
Function
Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).