Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human TGN46
Specificity
This antibody detects endogenous levels of TGN46 at Human, Mouse
Gene Name
TGOLN2 TGN46 TGN51
Protein Name
Trans-Golgi network integral membrane protein 2 (TGN38 homolog) (TGN46) (TGN48) (Trans-Golgi network protein TGN51)
Other Name
Species
Human
Gene ID
10618
Uniprot
O43493,
Species.1
Mouse
Gene ID.1
22135
Uniprot.1
Q62314
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cell membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Primarily in trans-Golgi network. Cycles between the trans-Golgi network and the cell surface returning via endosomes.
Tissue Expression
Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells.
Signaling_pathway
Research Areas
Function
May be involved in regulating membrane traffic to and from trans-Golgi network.