SKU: WP10980 Categories: ,

AIFL Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP10980-100
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Product details

Background:

domain:The Rieske domain induces apoptosis., function:Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential., similarity:Belongs to the FAD-dependent oxidoreductase family., similarity:Contains 1 Rieske domain., subcellular location:Does not translocate to the nucleus upon induction of apoptosis., tissue specificity:Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).,

Specifications

Size50μL/100μL
TargetAIFL
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)67kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human AIFM3. AA range:10-59
SpecificityAIFL Polyclonal Antibody detects endogenous levels of AIFL protein.
Gene NameAIFM3
Protein NameApoptosis-inducing factor 3
Other NameAIFM3; / AIFL; / Apoptosis-inducing factor 3; / Apoptosis-inducing factor-like protein
SpeciesHuman
Gene ID150209
UniprotQ96NN9,
Species.1Mouse
Gene ID.172168
Uniprot.1Q3TY86
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMitochondrion . Does not translocate to the nucleus upon induction of apoptosis.
Tissue ExpressionUbiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
Signaling_pathway
Research Areas
FunctionDomain:The Rieske domain induces apoptosis.,Function:Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.,similarity:Belongs to the FAD-dependent oxidoreductase family.,similarity:Contains 1 Rieske domain.,subcellular location:Does not translocate to the nucleus upon induction of apoptosis.,tissue specificity:Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).,
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