SKU: WP7640 Categories: ,

AK3L1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7640-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetAK4
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)25kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human AK3L1
SpecificityThis antibody detects endogenous levels of AK3L1 at Human, Mouse,Rat
Gene NameAK4 AK3 AK3L1
Protein NameAdenylate kinase isoenzyme 4, mitochondrial (ATP-AMP transphosphorylase) (Adenylate kinase 3-like)
Other Name
SpeciesHuman
Gene ID100507855
UniprotP27144,
Species.1Mouse
Gene ID.111639
Uniprot.1Q9WUR9,
Species.2Rat
Gene ID.229223
Uniprot.2Q9WUS0
Cellular LocalizationMitochondrion matrix .
Tissue ExpressionHighly expressed in kidney, moderately expressed in heart and liver and weakly expressed in brain.
Signaling_pathway
Research Areas
FunctionInvolved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates . Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor . Also displays broad nucleoside diphosphate kinase activity . Plays a role in controlling cellular ATP levels by regulating phosphorylation and activation of the energy sensor protein kinase AMPK . Plays a protective role in the cellular response to oxidative stress .
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