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Home/Reagents/Antibody/Primary antibody/Polyclonal Antibody/Rabbit pAb/AK5 Polyclonal Antibody
SKU: WP10989 Categories: ,

AK5 Polyclonal Antibody

Ucallm_WP10989-50

Price range: $268.00 through $328.00

SKU: WP10989-100
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Product details

Background:

adenylate kinase 5(AK5) Homo sapiens This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetAK5
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)25kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human AK5. AA range:391-440
SpecificityAK5 Polyclonal Antibody detects endogenous levels of AK5 protein.
Gene NameAK5
Protein NameAdenylate kinase isoenzyme 5
Other NameAK5; / Adenylate kinase isoenzyme 5; / AK 5; / ATP-AMP transphosphorylase 5
SpeciesHuman
Gene ID26289
UniprotQ9Y6K8,
Species.1Mouse
Gene ID.1229949
Uniprot.1Q920P5
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm .
Tissue ExpressionBrain specific.
Signaling_pathway
Research Areas>>Purine metabolism; / >>Thiamine metabolism; / >>Metabolic pathways; / >>Nucleotide metabolism; / >>Biosynthesis of cofactors
FunctionCatalytic activity:ATP + AMP = 2 ADP.,Function:Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP.,similarity:Belongs to the adenylate kinase family.,subunit:Monomer.,tissue specificity:Brain specific.,
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