AK5 Polyclonal Antibody
Ucallm_WP10989-50
Price range: $268.00 through $328.00
Product details
Background:
adenylate kinase 5(AK5) Homo sapiens This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | AK5 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 25kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human AK5. AA range:391-440 |
| Specificity | AK5 Polyclonal Antibody detects endogenous levels of AK5 protein. |
| Gene Name | AK5 |
| Protein Name | Adenylate kinase isoenzyme 5 |
| Other Name | AK5; / Adenylate kinase isoenzyme 5; / AK 5; / ATP-AMP transphosphorylase 5 |
| Species | Human |
| Gene ID | 26289 |
| Uniprot | Q9Y6K8, |
| Species.1 | Mouse |
| Gene ID.1 | 229949 |
| Uniprot.1 | Q920P5 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | Brain specific. |
| Signaling_pathway | |
| Research Areas | >>Purine metabolism; / >>Thiamine metabolism; / >>Metabolic pathways; / >>Nucleotide metabolism; / >>Biosynthesis of cofactors |
| Function | Catalytic activity:ATP + AMP = 2 ADP.,Function:Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP.,similarity:Belongs to the adenylate kinase family.,subunit:Monomer.,tissue specificity:Brain specific., |
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