Product details
Background:
AKAP7 rabbit pAb
Ucallm_WP6517-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | AKAP7 |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | 11kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human AKAP7 |
| Specificity | This antibody detects endogenous levels of AKAP7 at Human |
| Gene Name | AKAP7 AKAP15 AKAP18 |
| Protein Name | A-kinase anchor protein 7 isoforms alpha and beta (AKAP-7 isoforms alpha and beta) (A-kinase anchor protein 18 kDa) (AKAP 18) (Protein kinase A-anchoring protein 7 isoforms alpha/beta) (PRKA7 isoforms alpha/beta) |
| Other Name | |
| Species | Human |
| Gene ID | 9465 |
| Uniprot | O43687, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | O55074 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | [Isoform Alpha]: Lateral cell membrane; Lipid-anchor. Targeted predominantly to the lateral membrane.; [Isoform Beta]: Apical cell membrane; Lipid-anchor. Targeted predominantly to the apical membrane. |
| Tissue Expression | Expressed in brain, heart, lung, pancreas and skeletal muscle. |
| Signaling_pathway | |
| Research Areas | |
| Function | Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium. |
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