SKU: WP17117 Categories: ,

AL1L2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP17117-100
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Product details

Background:

This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010],

Specifications

Size50μL/100μL
TargetAL1L2
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)102kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human AL1L2 AA range: 74-124
SpecificityThis antibody detects endogenous levels of AL1L2 at Human/Mouse
Gene NameALDH1L2
Protein NameAL1L2
Other Name
SpeciesHuman
Gene ID160428
UniprotQ3SY69,
Species.1Mouse
Gene ID.1216188
Uniprot.1Q8K009
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMitochondrion .
Tissue ExpressionHighly expressed in pancreas, heart, brain and skeletal muscle.
Signaling_pathway
Research Areas>>One carbon pool by folate; / >>Metabolic pathways
FunctionCatalytic activity:10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH.,sequence Caution:Wrong choice of CDS.,similarity:Belongs to the aldehyde dehydrogenase family.,similarity:Contains 1 acyl carrier domain.,similarity:In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.,similarity:In the N-terminal section; belongs to the GART family.,
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