Name: ALB Monoclonal Antibody
SKU: WM0472
Price: 268 USD
Availability: InStock

ALB Monoclonal Antibody

Ucallm_WM0472-50

Price range: $268.00 through $328.00

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50μl

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SKU: WM0472-50

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Product details

Background:
This gene encodes the most abundant protein in human blood. This protein functions in the regulation of blood plasma colloid osmotic pressure and acts as a carrier protein for a wide range of endogenous molecules including hormones, fatty acids, and metabolites, as well as exogenous drugs. Additionally, this protein exhibits an esterase-like activity with broad substrate specificity. The encoded preproprotein is proteolytically processed to generate the mature protein. A peptide derived from this protein, EPI-X4, is an endogenous inhibitor of the CXCR4 chemokine receptor. [provided by RefSeq, Jul 2016],

Specifications

Size	50μL/100μL
Target	Albumin
Reactivity	Human
Applications	WB
MW(Calculated)	69kD
MW(Observed)
Host Species	Mouse
Isotype
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:1000-1:2000; Not yet tested in other applications.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	Affinity purification
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	18F10
Immunogen	Purified recombinant human ALB protein fragments expressed in E.coli.
Specificity	ALB Monoclonal Antibody detects endogenous levels of ALB protein.
Gene Name	ALB
Protein Name	ALB(Albumin)
Other Name	ALB; / GIG20; / GIG42; / Serum albumin
Species	Human
Gene ID	213
Uniprot	P02768,
Species.1	Mouse
Gene ID.1
Uniprot.1	P07724,
Species.2	Rat
Gene ID.2
Uniprot.2	P02770
Cellular Localization	Secreted.
Tissue Expression	Plasma.
Signaling_pathway
Research Areas	>>Thyroid hormone synthesis
Function	Caution:A peptide arising from positions 166 to 174 was originally (PubMed:3087352 and PubMed:2437111) termed neurotensin-related peptide (NRP) or kinetensin and was thought to regulates fat digestion, lipid absorption, and blood flow.,Disease:A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood [MIM:194470].,Disease:Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.,Function:Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood.,miscellaneous:Acetylated on Lys-223 by acetylsalicylic acid.,online information:Serum albumin entry,polymorphism:The sequence shown is that of variant albumin A.,PTM:Glycated in diabetic patients.,PTM:Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.,similarity:Belongs to the ALB/AFP/VDB family.,similarity:Contains 3 albumin domains.,tissue specificity:Plasma.,