SKU: WR4350 Categories: ,

U-Blot® Albumin Rabbit mAb

Price range: $268.00 through $328.00

SKU: WR4350-50
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Product details

Background:This gene encodes the most abundant protein in human blood. This protein functions in the regulation of blood plasma colloid osmotic pressure and acts as a carrier protein for a wide range of endogenous molecules including hormones, fatty acids, and metabolites, as well as exogenous drugs. Additionally, this protein exhibits an esterase-like activity with broad substrate specificity. The encoded preproprotein is proteolytically processed to generate the mature protein. A peptide derived from this protein, EPI-X4, is an endogenous inhibitor of the CXCR4 chemokine receptor. [provided by RefSeq, Jul 2016],

Specifications

Size50μL/100μL
TargetAlbumin
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, IP, ELISA
MW(Calculated)69kD
MW(Observed)69kD
Host SpeciesRabbit
IsotypeIgG,Kappa
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:500-1:2000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
PurificationRecombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberRM0561R
ImmunogenThe specific immunogen used to produce this antibody is proprietary information.
SpecificityEndogenous
Gene NameALB
Protein NameALB(Albumin)
Other NameALB; / GIG20; / GIG42; / Serum albumin
SpeciesHuman
Gene ID213
UniprotP02768,
Species.1Mouse
Gene ID.1
Uniprot.1P07724,
Species.2Rat
Gene ID.2
Uniprot.2P02770
Cellular LocalizationSecreted
Tissue ExpressionPlasma.
Signaling_pathway
Research Areas>>Thyroid hormone synthesis
FunctionCaution:A peptide arising from positions 166 to 174 was originally (PubMed:3087352 and PubMed:2437111) termed neurotensin-related peptide (NRP) or kinetensin and was thought to regulates fat digestion, lipid absorption, and blood flow.,disease:A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood [MIM:194470].,disease:Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.,Function:Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood.,miscellaneous:Acetylated on Lys-223 by acetylsalicylic acid.,online information:Serum albumin entry,polymorphism:The sequence shown is that of variant albumin A.,PTM:Glycated in diabetic patients.,PTM:Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.,similarity:Belongs to the ALB/AFP/VDB family.,similarity:Contains 3 albumin domains.,tissue specificity:Plasma.,
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