Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human ANKRD16
Specificity
This antibody detects endogenous levels of ANKRD16 at Human, Mouse,Rat
Gene Name
ANKRD16
Protein Name
Ankyrin repeat domain-containing protein 16
Other Name
Species
Human
Gene ID
54522
Uniprot
Q6P6B7,
Species.1
Mouse
Gene ID.1
320816
Uniprot.1
A2AS55,
Species.2
Rat
Gene ID.2
307102
Uniprot.2
Q499M5
Cellular Localization
Cytoplasm . Nucleus .
Tissue Expression
Signaling_pathway
Research Areas
Function
Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides.