Price range: $268.00 through $328.00
Background:
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1, 2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | Annexin III |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 36kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Annexin III. AA range:15-64 |
| Specificity | Annexin III Polyclonal Antibody detects endogenous levels of Annexin III protein. |
| Gene Name | ANXA3 |
| Protein Name | Annexin A3 |
| Other Name | ANXA3; / ANX3; / Annexin A3; / 35-alpha calcimedin; / Annexin III; / Annexin-3; / Inositol 1; / 2-cyclic phosphate 2-phosphohydrolase; / Lipocortin III; / Placental anticoagulant protein III; / PAP-III |
| Species | Human |
| Gene ID | 306 |
| Uniprot | P12429, |
| Species.1 | Mouse |
| Gene ID.1 | 11745 |
| Uniprot.1 | O35639 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | cytoplasm,plasma membrane,membrane,axon,dendrite,phagocytic vesicle membrane,specific granule,neuronal cell body,extracellular exosome, |
| Tissue Expression | Aorta endothelial cell,Cervix,Colon carcinoma,Platelet, |
| Signaling_pathway | |
| Research Areas | |
| Function | Domain:A pair of annexin repeats may form one binding site for calcium and phospholipid.,Function:Inhibitor of phospholipase A2, also possesses anti-coagulant properties. Also cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate.,similarity:Belongs to the annexin family.,similarity:Contains 4 annexin repeats., |
