Name: ANR28 Polyclonal Antibody
SKU: WP0465
Price: 268 USD
Availability: InStock

ANR28 Polyclonal Antibody

Ucallm_WP0465-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP0465-100

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Product details

Background:

function:Putative regulatory subunit of protein phospatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation., similarity:Contains 27 ANK repeats., subcellular location:Seems to be excluded from nucleoli., subunit:Protein phospatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS). Interacts with PPP1C and HNRPK. Interacts with PPP6C, SAPS1 and SAPS3.,

Specifications

Size	50μL/100μL
Target	ANR28
Reactivity	Human, Mouse
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	115kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000; ELISA 1:5000-20000
Formulation	Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human protein . at AA range: 980-1060
Specificity	ANR28 Polyclonal Antibody detects endogenous levels of protein.
Gene Name	ANKRD28 KIAA0379
Protein Name	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK)
Other Name
Species	Human
Gene ID	23243
Uniprot	O15084,
Species.1	Mouse
Gene ID.1
Uniprot.1	Q505D1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Nucleus, nucleoplasm . Seems to be excluded from nucleoli.
Tissue Expression	Amygdala,Brain,PCR rescued clones,Testis,
Signaling_pathway
Research Areas
Function	Function:Putative regulatory subunit of protein phospatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation.,similarity:Contains 27 ANK repeats.,subcellular location:Seems to be excluded from nucleoli.,subunit:Protein phospatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS). Interacts with PPP1C and HNRPK. Interacts with PPP6C, SAPS1 and SAPS3.,