SKU: WP7545 Categories: ,

AP3M1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7545-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetAP3M1
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)46kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human AP3M1
SpecificityThis antibody detects endogenous levels of AP3M1 at Human, Mouse,Rat
Gene NameAP3M1
Protein NameAP-3 complex subunit mu-1 (AP-3 adapter complex mu3A subunit) (Adapter-related protein complex 3 mu-1 subunit) (Mu-adaptin 3A) (Mu3A-adaptin)
Other Name
SpeciesHuman
Gene ID26985
UniprotQ9Y2T2,
Species.1Mouse
Gene ID.155946
Uniprot.1Q9JKC8,
Species.2Rat
Gene ID.2
Uniprot.2P53676
Cellular LocalizationGolgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side . Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. .
Tissue Expression
Signaling_pathwayCellular Processes >> Transport and catabolism >> Lysosome
Research Areas
FunctionPart of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
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