SKU: WP7905 Categories: ,

AP3S2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7905-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetAP3S2
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)21kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human AP3S2
SpecificityThis antibody detects endogenous levels of AP3S2 at Human, Mouse
Gene NameAP3S2
Protein NameAP-3 complex subunit sigma-2 (AP-3 complex subunit sigma-3B) (Adapter-related protein complex 3 sigma-2 subunit) (Sigma-3B-adaptin) (Sigma3B-adaptin) (Sigma-adaptin 3b)
Other Name
SpeciesHuman
Gene ID10239
UniprotP59780,
Species.1Mouse
Gene ID.111778
Uniprot.1Q8BSZ2
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationGolgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side . Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. .
Tissue ExpressionPresent in all adult tissues examined.
Signaling_pathwayCellular Processes >> Transport and catabolism >> Lysosome
Research Areas
FunctionPart of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
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