SKU: WP11082 Categories: ,

ApoL1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11082-100
Enter the quantity you would like, or drag the panel to find the quantity and price that best for you
Bulk QuoteAuthorize OEM & ODM

Product details

Background:

This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008],

Specifications

Size50μL/100μL
TargetApoL1
ReactivityHuman
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)44kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human APOL1. AA range:261-310
SpecificityApoL1 Polyclonal Antibody detects endogenous levels of ApoL1 protein.
Gene NameAPOL1
Protein NameApolipoprotein L1
Other NameAPOL1; / APOL; / Apolipoprotein L1; / Apolipoprotein L; / Apo-L; / ApoL; / Apolipoprotein L-I; / ApoL-I
SpeciesHuman
Gene ID8542
UniprotO14791
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationSecreted.
Tissue ExpressionPlasma. Found on APOA-I-containing high density lipoprotein (HDL3). Expressed in pancreas, lung, prostate, liver, placenta and spleen.
Signaling_pathway
Research Areas>>African trypanosomiasis
FunctionFunction:May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.,sequence Caution:Translated as Gln.,similarity:Belongs to the apolipoprotein L family.,subunit:In plasma, interacts with APOA1 and mainly associated with large high density lipoprotein particles.,tissue specificity:Plasma. Found on APOA-I-containing high density lipoprotein (HDL3). Expressed in pancreas, lung, prostate, liver, placenta and spleen.,
Please login to post questions
Back to Top
Product has been added to your cart