Price range: $268.00 through $328.00
Background:
domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA)., function:Aquaporins facilitate the transport of water and small neutral solutes across cell membranes., similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily., tissue specificity:Expressed at low levels in roots and leaves.,
| Size | 50μL/100μL |
| Target | AQP11 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 26kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from AQP11 . at AA range: 130-210 |
| Specificity | AQP11 Polyclonal Antibody detects endogenous levels of AQP11 protein. |
| Gene Name | AQP11 |
| Protein Name | Aquaporin-11 |
| Other Name | AQP11; / AQPX1; / PSEC0027; / Aquaporin-11; / AQP-11 |
| Species | Human |
| Gene ID | 282679 |
| Uniprot | Q8NBQ7, |
| Species.1 | Mouse |
| Gene ID.1 | 66333 |
| Uniprot.1 | Q8BHH1, |
| Species.2 | Rat |
| Gene ID.2 | 286758 |
| Uniprot.2 | Q8CHM1 |
| Cellular Localization | Cytoplasmic vesicle membrane; Multi-pass membrane protein . Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein . Cytoplasm . Cytoplasm, perinuclear region . Localizes mainly to the periphery of lipid droplets (PubMed:24845055). it accumulates partly in mitochondrial-associated endoplasmic reticulum membranes (PubMed:31546170). . |
| Tissue Expression | Detected in the sperm head and tail (at protein level) (PubMed:28042826). Expressed in subcutaneous adipocytes (PubMed:24845055). Expressed in testis, kidney and ejaculated spermatozoa (PubMed:19812234). |
| Signaling_pathway | |
| Research Areas | |
| Function | Domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,Function:Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.,tissue specificity:Expressed at low levels in roots and leaves., |
