Product details
Background:
AQR rabbit pAb
Ucallm_WP7636-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | AQR |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 163kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human AQR |
| Specificity | This antibody detects endogenous levels of AQR at Human, Mouse |
| Gene Name | AQR KIAA0560 |
| Protein Name | Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160) |
| Other Name | |
| Species | Human |
| Gene ID | 9716 |
| Uniprot | O60306, |
| Species.1 | Mouse |
| Gene ID.1 | 11834 |
| Uniprot.1 | Q8CFQ3 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Nucleus, nucleoplasm . Localizes to speckle-like regions of the nucleoplasm. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Involved in pre-mRNA splicing as component of the spliceosome . Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis . Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly . May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing . Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3' overhang (in vitro) . |
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